Efficacy, Safety, and Plasma Pharmacokinetics of Escalating Dosages of Intravenously Administered Ravuconazole Lysine Phosphoester for Treatment of Experimental Pulmonary Aspergillosis in Persistently Neutropenic Rabbits.

Stomacher® 80 used to process lung tissue in antifungal drug trial for Aspergillus fumigatus.The Stomacher® 80 blending action selected for extraction of fungal spores post drug exposure. Continue reading

Enhanced Immunogenicity to Mycobacterium tuberculosis by Vaccination with an Alphavirus Plasmid Replicon Expressing Antigen 85A

The Stomacher® 80 was used to blend lungs and spleens of sacrificed animals. The study found that even with the optimum dose of the vaccine there was no further or enhanced protection against m.b tuberculosis.

clinical microbiology plasmid DNA vaccination lung spleen mycobacterium tuberculosis stomacher 80

Optimization of Periprosthetic Culture for Diagnosis of Propionibacterium acnes Prosthetic Joint Infection

Tissue specimens were homogenized in 3 ml of sterile saline using a Seward Stomacher 80, and the sterility of each vial of saline was confirmed at the time of use by bacterial
culture.

These results support the need for a minimum culture incubation period of 13 days to be applied to both aerobic and anaerobic culture media for all periprosthetic specimens. Optimal recovery of infecting organisms from PJI specimens will be an important component in generating a universal definition for PJI due to indolent agents of infection, such as P. acnes.

clinical microbiology prosthetic joint propionibacterium stomacher 80

Development and Validation of a Quantitative Real-Time PCR Assay Using Fluorescence Resonance Energy Transfer Technology for Detection of Aspergillus fumigatus in Experimental Invasive Pulmonary Aspergillosis

Lung tissue in each individual rabbit was sampled and cultured by excision of a representative region of the lung. Each fragment was weighed individually, placed in sterile stomacher® bags, and homogenized with sterile saline for 15 s per tissue sample in a Stomacher® 80.

clinical microbiology pulmonary lung aspergillus fumigatus stomacher 80